Fluorous tagged small molecule microarrays
Nicholson, Rebecca L.; Ladlow, Mark L.; Spring, David R.; Nicholson Rebecca L.; Department of Chemistry, University of Cambridge; Ladlow Mark L.; GSK Cambridge Technology Centre; Spring David R.; Department of Chemistry, University of Cambridge
Журнал:
Chemical Communications
Дата:
2007
Аннотация:
The affinity fluorous interaction between fluorous tagged small molecules and a fluoroalkyl modified glass surface was shown to facilitate the detection of proteinâ ligand binding interactions in the fabrication and screening of small molecule microarrays.
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