The Fries Reaction
MAREY, ABDEL FATTAH; BADDAR, FAWZY G.; AWAD, WILLIAM I.
Журнал:
Nature
Дата:
1953
Аннотация:
IN continuation of the study of the mechanism of the Fries reaction<sup>1</sup>, a systematic investigation of the effect of medium on the rearrangement of phenyl (I; R=H)- and p-cresyl(I ; R=CH3)-hydrogen succinate in presence of anhydrous aluminium chloride has been carried out. The reaction was accomplished under standardized conditions using a constant temperature (117°, boiling n-butyl alcohol bath) for 2½ hr., the same molecular proportion of the ester (0.033 mole), aluminium chloride (0.067 mole) and the solvent (0.462 mole). The results are summarized in Table 1.
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