Effect of Valinomycin on Net Sodium and Potassium Transport in Ehrlich Ascites Tumour Cells
LEVINSON, CHARLES
Журнал:
Nature
Дата:
1967
Аннотация:
GORDON et al.<sup>1</sup> speculated that in the mitochondria of intact tumour cells there is a mechanism dependent on valinomycin for the uptake of potassium directly from the cell environment. This mechanism is thought to act independently of the plasma membrane potassium ion transport system. It is well known that in the presence of valinomycin isolated mitochondria accumulate large amounts of potassium ions<sup>2</sup>. Thus the demonstration of potassium ion uptake which is independent of the plasma membrane localized mechanism in the intact cell would be very interesting.
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